Senior Vice President, Sales & Marketing

Position Title:  Senior Vice President, Sales & Marketing

Location: Remote

Reports to: Chief Commercial Officer

Department: Commercial

Cabaletta Bio (Nasdaq: CABA) is a late-stage clinical biotechnology company focused on developing and launching curative targeted cell therapies designed specifically for patients with autoimmune diseases. The CABA™ platform encompasses two complementary strategies which aim to advance the discovery and development of engineered T cell therapies with the potential to become deep and durable, perhaps curative, treatments for a broad range of autoimmune diseases. The lead CARTA (Chimeric Antigen Receptor T cells for Autoimmunity) strategy is prioritizing the development of rese-cel, a 4-1BB-containing fully human CD19-CAR T cell investigational therapy. Rese-cel is currently being evaluated in the RESET™ (REstoring SElf-Tolerance) clinical development program spanning multiple therapeutic areas, including rheumatology, neurology and dermatology. Cabaletta Bio’s headquarters and labs are located in Philadelphia, PA. For more information, please visit www.cabalettabio.com and connect with us on LinkedIn.

Uniquely Differentiated. Rapid. Elegant.

At Cabaletta, we are driven by the shared mission of developing cures, where a patients’ own cells are used to fight disease. We are building a culture grounded in the knowledge that successful cures can be achieved for patients if every member of the Cabaletta is focused on the success of the team. To nurture this, we make an active commitment to the well-being and continuous growth of each employee who joins the team. In this way, we are not only working to improve the lives of patients, but of everyone involved. #CabalettaCrew. 

We’re proud to be a Great Place to Work-Certified™ company! #GPTWcertified Check out what our employees say makes working here so great:  Working at Cabaletta Bio Inc | Great Place to Work®

About the Position:

The Senior Vice President, Sales & Marketing will report to the Chief Commercial Officer and play a critical leadership role in preparing Cabaletta Bio for the anticipated launch of rese-cel in dermatomyositis. This individual will be responsible for building and leading the Sales and Marketing organization, developing commercial capabilities, and executing launch readiness activities in close partnership with the CCO and cross-functional stakeholders.

The SVP will oversee sales, marketing, commercial operations, and field execution to ensure a successful and compliant launch. Working collaboratively with Medical Affairs, Market Access, Operations, Manufacturing, IT, Regulatory, and Compliance, this leader will help translate commercial strategy into operational execution, establishing the infrastructure, processes, and capabilities required to commercialize a complex autologous cell therapy.  This highly visible leadership role requires deep expertise in specialty biologics and cell therapy commercialization, with experience leading commercial teams and supporting successful product launches. The ideal candidate will bring strong strategic thinking, operational excellence, and a proven ability to build high-performing organizations in a growth-stage biotechnology environment.

Responsibilities:

Commercial Strategy & Execution

• Partner with the Chief Commercial Officer to develop and execute the commercial strategy for rese-cel, including market development, customer engagement, brand strategy, and launch readiness activities.
• Lead commercialization planning and execution to ensure successful launch preparation and market adoption.
• Translate commercial strategy into actionable sales and marketing plans, objectives, and performance metrics.
• Provide customer, market, and competitive insights to inform commercial decision-making and launch planning.
• Support forecasting, business planning, and commercial analytics activities.

Sales & Marketing Leadership

• Build, lead, and develop a high-performing Sales and Marketing organization capable of supporting a successful launch and long-term growth.
• Develop organizational structure, hiring plans, talent strategies, and capability-building programs for commercial functions.
• Establish performance expectations and foster a culture of accountability, collaboration, and execution excellence.

Cell Therapy Commercialization & Launch Readiness

• Lead launch planning and execution for rese-cel, including field force design, deployment strategy, promotional planning, customer engagement, and treatment center activation.
• Partner with Market Access to support payer engagement strategies, reimbursement readiness, and site-of-care considerations.
• Collaborate with Operations, Manufacturing, and Patient Services teams to ensure commercial readiness for the unique logistical and operational requirements of cell therapy delivery.
• Help establish customer-facing processes supporting patient identification, treatment center engagement, scheduling, chain of identity, and chain of custody.

Cross-Functional Leadership

• Partner closely with Medical Affairs to ensure scientifically accurate and compliant promotional messaging and educational initiatives.
• Collaborate with IT to develop and implement commercial systems, CRM platforms, order management capabilities, and analytics tools required to support launch execution.
• Work closely with Regulatory, Legal, Compliance, and Quality partners to ensure all commercial activities meet applicable legal and regulatory requirements.
• Serve as a key member of the Commercial Leadership Team and contribute to broader company initiatives and strategic planning.

External Stakeholder Engagement

• Build and maintain strong relationships with key opinion leaders, treatment centers, advocacy organizations, and other critical stakeholders.
• Represent the company at industry, scientific, and commercial meetings as appropriate.
• Monitor market dynamics, competitive activities, and evolving customer needs to identify opportunities and risks.

Financial Management

• Develop and manage commercial budgets and resource plans in alignment with organizational priorities.
• Ensure effective and efficient deployment of commercial investments to achieve launch and business objectives.

Required Qualifications:

• Bachelor's degree required; advanced degree (MBA, PharmD, MD, or other relevant graduate degree) preferred.
• Minimum 15 years of progressive commercial experience within biotechnology, biopharmaceuticals, or specialty pharmaceuticals.
• Significant commercial leadership experience with a demonstrated track record of building, scaling, and leading successful sales and marketing organizations.
• Experience supporting, leading, or executing a product launch in cell therapy, gene therapy, or another complex specialty therapeutic area.
• Deep understanding of cell therapy commercialization, including treatment center engagement, patient access, operational logistics, chain of identity, and chain of custody requirements.
• Demonstrated success partnering across Medical Affairs, Market Access, Operations, IT, Regulatory, and Compliance functions.
• Strong financial, analytical, and business planning capabilities.

Preferred Qualifications:

• Direct commercialization and/or launch experience in CAR-T or other autologous cell therapies.
• Experience in rare disease, immunology, rheumatology, autoimmune disease, or other specialty therapeutic categories.
• Experience working in a clinical-stage or growth-stage biotechnology company preparing for its first commercial launch.

Our name – Cabaletta – is derived from the operatic term that represents a rapid, repetitive, and technically challenging section of an operatic aria, designed to showcase the skills of the lead singer. Analogously, Cabaletta Bio strives to achieve rapid and repetitive product development, building on our indication prioritization and biologic platform that targets the driver of specific autoimmune diseases without the need for long-term immunosuppression.

For more information, please visit  https://www.cabalettabio.com/join-our-crew

Our most important asset is our people, and we offer competitive benefits, PTO, and stock option plans.

Cabaletta Bio is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability, protected veteran status or any other basis protected by applicable law.

Cabaletta Bio, Inc. does not accept unsolicited resumes from recruiters, employment agencies, or staffing firms. To conduct business with Cabaletta, a Master Services Agreement (MSA) must be executed and confirmed prior to submitting any information relating to a potential candidate. Without a signed MSA, Cabaletta shall not be responsible to any individual or entity for any payment relating to any form of fee or compensation.

And, if a resume or candidate is submitted by a recruiter, an employment agency, or a staffing firm without a fully executed MSA, Cabaletta has the unrestricted right to pursue and hire any of those candidate(s) without any legal or financial responsibility to the recruiter, agency, and/or firm.

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