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Syneos Health

Principal Biostatistician - Biomarker - open to various countries in Europe

Posted 3 days ago
5-10 years experience
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AI Summary

Collaborate with cross-functional teams to plan, execute, and analyze biomarker aspects of clinical studies. Develop biomarker evaluation plans and provide statistical input using advanced AI and machine learning approaches.

Principal Biostatistician - Biomarker - open to various countries in Europe

Syneos Health® is a leading fully-integrated life sciences services organization built to accelerate customer success. We partner with innovators at every point across the drug development and commercialization continuum, helping them navigate complexity, anticipate change and accelerate progress.
 
Our Clinical Solutions team members act with a drug development mindset, applying their years of experience and deep expertise to truly understand customer needs and represent those in the solutions we shape.
 
Whether you join us in a Functional Service Provider partnership or a Full-Service environment, you’ll collaborate with passionate problem solvers, innovating as a team to help our customers achieve their goals. We are agile and driven to deliver – for one another, our customers, and, most importantly, for those in need.
 
Discover what your 25,000 future colleagues already know:
 
Why Syneos Health
• We are passionate about developing our people, through career development and progression; supportive and engaged line management; technical and therapeutic area training; peer recognition and total rewards program.
• We are committed to building an inclusive culture – where you can authentically be yourself. Central to this is our purpose – Driven to Deliver – which captures the passion of our colleagues to show up each day and shape solutions that have the ability to dramatically impact someone’s life. 
• We are continuously building the company we all want to work for and our customers want to work with. Why? Because we know that when we bring together smart colleagues from across the world, we can shape the future of healthcare, driving impact for customers and defining the pace of patient progress. 

Job Responsibilities

Major tasks:  

  • Collaborates with representatives from other functions to plan, execute and analyze all biomarker aspects (including genomics) of clinical studies or biomarker studies in the role of the biomarker statistician and assumes the role of project biomarker statistician under guidance of an experienced statistician  

  • Develops the Biomarker Evaluation Plan for the study as appropriate, ensuring overall consistency within and between projects  

  • Provides statistical input in clinical development discussions, and usage of AI and ML approaches.   

  • Facilitates the overall organization and coordination of statistical activities regarding biomarker research and development activities for specific studies and projects  

  • Conduct and design advanced data analysis for genomics and biomarker statistics, including statistical programming, and design complex analysis algorithms.  

  • Experience with RNA, olink and other biomarker data handling experience 

  • Assumes responsibility for the production and accuracy of the Biomarker Evaluation Report with respect to statistical deliverables and interpretation of the results.  

  • Works independently at routine and complex statistical questions, modeling and tasks.  

  • Develops and implements standard processes for the analysis of routine (parts of) biomarker assessments.  

  

  

Qualifications  

 · PhD or MSc in Biostatistics, Statistics or Mathematics, or related field  

 · Strong communication and interpersonal skills  

 · Ability to work independently as well as collaboratively, as required.  

· Minimal supervision required.  

· Usage of AI and ML approaches   

· Previous experience in independently leading biomarker study mandatory 

 · Previous clinical trial experience, industry experience is preferred 

· Strong knowledge on Biomarker evaluation, esp. In immunology and infections, type I diabetes, relevant parameters and underlying biology  

 · Good knowledge of statistical programming languages including R (Bioconductor package and other relevant R packages for genetic data), Python  

 · Analysis of high-dimensional data  

Get to know Syneos Health


Over the past 5 years, we have worked with 94% of all Novel FDA Approved Drugs, 95% of EMA Authorized Products and over 200 Studies across 73,000 Sites and 675,000+ Trial patients.

No matter what your role is, you’ll take the initiative and challenge the status quo with us in a highly competitive and ever-changing environment. Learn more about Syneos Health.

http://www.syneoshealth.com

Additional Information


Tasks, duties, and responsibilities as listed in this job description are not exhaustive.  The Company, at its sole discretion and with no prior notice, may assign other tasks, duties, and job responsibilities. Equivalent experience, skills, and/or education will also be considered so qualifications of incumbents may differ from those listed in the Job Description.  The Company, at its sole discretion, will determine what constitutes as equivalent to the qualifications described above.   Further, nothing contained herein should be construed to create an employment contract.  Occasionally, required skills/experiences for jobs are expressed in brief terms.  Any language contained herein is intended to fully comply with all obligations imposed by the legislation of each country in which it operates, including the implementation of the EU Equality Directive, in relation to the recruitment and employment of its employees.  The Company is committed to compliance with the Americans with Disabilities Act, including the provision of reasonable accommodations, when appropriate, to assist employees or applicants to perform the essential functions of the job.

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