Senior Project Manager

POSITION TITLE: Senior Project Manager

LOCATION: Spain (Remote)

This position reports to our global HQ in Cambridge, MA and is remote.

Who We Are: 
TriNetX connects healthcare organizations and researchers across the globe so they can see what’s happening in real patient populations—not guesses, not simulations.
Our aim is simple and ambitious: Provide a clear path to trustworthy answers, whether your goal is to create promising new therapies, publish groundbreaking research, or improve health outcomes.
We keep identifiable data where it belongs—inside more than 11,000+ clinical sites across 20+ countries—preserving security, provenance, and granularity. Our trusted partnerships with providers ensure high-fidelity data, and a properly governed linkage back to individual patients.
At TriNetX, we enable life sciences, healthcare, and academic institutions to strengthen human health—with data you can trace, evidence you can defend, and answers you can trust.

Who We Are Looking For:  

TriNetX is seeking an experienced Senior Project Manager to lead and govern a growing portfolio of projects funded by the European Commission (Horizon Europe, Horizon 2020), IMI/IHI, and other regulatory or public-sector funding bodies. This individual will serve as the primary operational owner for funded project delivery, ensuring compliance with grant agreements, maintaining funder relationships, driving cross-functional execution, and protecting both scientific and commercial commitments across multi-year programmes.  The role sits within the Client Delivery Project Management Office (cPMO) and partners closely with, Finance, Legal, and other cross functional teams.

What You Will Be Doing:

Portfolio Governance & Delivery

• Own end-to-end delivery of an assigned portfolio of EU Commission and regulatory-funded projects, from kick-off through final reporting and closeout. 
• Develop and maintain integrated project plans, work breakdown structures, milestone schedules, and risk registers across concurrent projects. 
• Apply the Project Monitoring & Controlling SOP and RYG status frameworks to track progress, surface variances early, and drive corrective action. 
• Coordinate internal workstreams and client-facing teams to ensure on-time, on-scope delivery. 

Grant Compliance & Funder Management 

• Ensure full compliance with EU grant regulations including EC Grant Agreements, General Conditions, and applicable Financial Regulations (e.g., H2020/Horizon Europe rules for participation). 
• Oversee preparation and submission of periodic technical and financial reports to the European Commission and other funding bodies. 
• Serve as the primary point of contact for Project Officers, coordinators, and external auditors; manage responses to audit queries. 
• Monitor eligible expenditure, track budget consumption against approved work packages, and flag deviations in coordination with Finance. 
• Support DCAA/FAR Part 31 or equivalent cost accounting requirements where applicable to sub-award or transatlantic funding structures.

Consortium & Stakeholder Coordination

• Manage relationships with consortium partners including academic institutions, hospitals, SMEs, and other industry stakeholders across EU member states. 
• Facilitate Consortium Board and General Assembly meetings as needed; prepare and distribute minutes, action logs, and governance documentation. 
• Negotiate scope and timeline adjustments with partners and funders through formal amendment processes (e.g., Grant Agreement Amendments). 
• Represent TriNetX at funder review meetings, project review boards, and relevant EU-funded events. 

Commercial & Financial Oversight 

• Manage project-level budgets and margin targets; ensure revenue recognition is aligned with project milestones and deliverable acceptance. 
• Partner with Finance to maintain accurate cost forecasting and margin tracking across the funded portfolio. 
• Identify and escalate scope creep, budget risk, or eligibility concerns before they impact financial performance or funder compliance. 
• Support proposal and bid processes for new EU or regulatory-funded opportunities, including budget development and staffing models. 

Process Improvement & AI Integration 

• Champion the adoption of AI-assisted project management tools and workflows within the cPMO to drive efficiency and quality. 
• Contribute to the development of scalable PMO frameworks, templates, and reporting standards applicable across funded and commercial projects. 
• Mentor junior project managers and analysts; foster a culture of accountability, transparency, and continuous improvement.

Tools and Systems

• Utilize systems such as Jira, Confluence, MS Teams, Slack, Zoom, SharePoint, Salesforce, Certinia/FinancialForce.  

What You Bring to TriNetX:

• 7+ years of project management experience, with at least 3 years managing EU-funded projects (Horizon 2020, Horizon Europe, IMI/IHI, or similar). 
• Demonstrated experience with EC Grant Agreement compliance, technical and financial reporting to the European Commission, and audit management. 
• Strong command of project financial management: budget tracking, eligible cost categories, indirect cost models, and funder reporting. 
• Experience managing multi-partner consortia across international, cross-functional stakeholder groups. 
• Proficiency with project management methodologies (PMP, PRINCE2, or equivalent); milestone-based reporting. 
• Exceptional written and verbal communication skills in English; ability to produce executive-quality documentation for senior stakeholders and funders.
• Proficiency in MS Office

Bonus Points

• Background in life sciences, health informatics, real-world evidence, or clinical research — particularly within a for-profit subcontractor context. 
• Experience with IHI Joint Undertaking, EMA regulatory programmes, or other EU regulatory-adjacent funding bodies. 
• Knowledge of TriNetX's federated network model and real-world data research use cases (or comparable RWD/RWE platforms). 
• Proficiency in a second EU language (German, French, Italian, or Spanish particularly valued). 
• PMP, PRINCE2 Practitioner, or MSP certification

Learn more about TriNetX:

To learn more about us, please check out our website, blog, and Careers page - and be sure to follow us on LinkedIn. 

Interested in joining our community?

TriNetX is an Equal Opportunity Employer. All persons are considered for employment without regard to their race, color, creed, religion, national origin, ancestry, citizenship status, age, disability or handicap, sex or gender, marital status, sexual orientation, genetic information, gender identity, veteran status, or any other characteristic or status protected by applicable federal, state or local laws.

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