Sr. Manufacturing Connectivity Solution Architect

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Ready to explore, break barriers, and discover more? We know you’ve got big plans – so do we! Our colleagues across the globe love innovating with science and technology to enrich people’s lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.  

This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the US. 

Your Role:

MilliporeSigma is seeking a highly experienced Sr. Connectivity Solution Architect to join our Smart Manufacturing and Digital Platforms organization.

This role is responsible for designing and governing connectivity solutions that enable seamless integration between manufacturing, laboratory, warehouse, facility, and enterprise business systems. The architect will play a key role in advancing MilliporeSigma's digital transformation strategy by ensuring reliable, secure, and scalable data flows across the enterprise.

Working closely with business stakeholders, site teams, enterprise architects, engineers, and technology partners, the Senior Connectivity Solution Architect will establish standardized integration patterns, define connectivity standards, and drive the implementation of enterprise-wide solutions that support manufacturing operations, analytics, automation, and data-driven decision making.

Key Responsibilities

Solution Architecture & Design

• Design and implement enterprise connectivity solutions linking manufacturing, laboratory, warehouse, and facility systems with enterprise applications.
• Define scalable integration architectures supporting real-time and near real-time data exchange across business and operational environments.
• Establish reusable connectivity patterns, standards, and best practices that can be deployed across multiple sites and business functions.
• Ensure solution designs align with enterprise architecture, cybersecurity, data governance, and compliance requirements.
• Drive adoption of modern integration technologies, event-driven architectures, and cloud-enabled data platforms.

Enterprise & Manufacturing Systems Integration

• Design and support integrations between enterprise applications and manufacturing systems, including MES, LIMS, ERP, historians, analytics platforms, and cloud services.
• Develop and validate integration solutions utilizing APIs, messaging technologies, industrial connectivity platforms, and middleware solutions.
• Configure and support connectivity platforms such as KEPServerEX and related technologies to enable secure data acquisition and exchange.
• Partner with site teams and technology vendors to deploy standardized connectivity solutions.
• Support implementation of Unified Namespace (UNS), MQTT, and Industry 4.0 connectivity frameworks where appropriate.

Technical Leadership

• Collaborate with enterprise architects, infrastructure teams, cybersecurity teams, and manufacturing technology organizations to deliver integrated solutions.
• Lead technical design reviews and provide architecture guidance throughout project lifecycles.
• Develop and maintain reference architectures, implementation standards, technical documentation, and reusable templates.
• Evaluate emerging technologies and recommend solutions that improve scalability, reliability, and business value.

Delivery & Operational Support

• Support solution deployment, testing, validation, and user acceptance activities.
• Provide advanced troubleshooting and technical support for connectivity-related issues.
• Monitor integration performance and identify opportunities for continuous improvement.
• Facilitate knowledge transfer and support operational handoff to site and support teams.
• Contribute to operational procedures, runbooks, and support documentation.

Prefer to sit in St. Louis, Boston or Temecula. Fully remote

Who You Are

Minimum Qualifications:

• Bachelor's degree in Computer Science, Information Technology, Engineering, Automation, or a related technical discipline.

• 10+ years of experience in solution architecture, systems integration, manufacturing technology, or enterprise connectivity.
• Proven experience designing and implementing complex integrations across enterprise and manufacturing environments.
• Experience working in pharmaceutical, biotechnology, life sciences, medical device, or other regulated industries preferred.
• Demonstrated ability to lead cross-functional technical initiatives and collaborate across global organizations.

Preferred Qualifications:

• Master's degree preferred.

Enterprise Systems

Experience integrating and supporting enterprise platforms such as:

• SAP ERP (ECC and/or S/4HANA)
• Manufacturing Execution Systems (MES)
• Laboratory Information Management Systems (LIMS)
• Electronic Batch Records (EBR)
• Enterprise Asset Management (EAM)
• Quality Management Systems (QMS)
• Data Historians
• Data Lakes and Analytics Platforms
• Cloud Services and Integration Platforms

Integration Technologies

Strong understanding of:

• API-based integrations
• REST and Web Services
• Event-Driven Architecture (EDA)
• Service-Oriented Architecture (SOA)
• Messaging technologies including MQTT
• Middleware and integration platforms
• Data modeling and transformation

Connectivity & Industrial Technologies

Working knowledge of:

• KEPServerEX
• OPC UA
• Industrial communication standards
• Manufacturing and laboratory equipment connectivity
• Historian platforms such as AVEVA PI / OSIsoft PI
• ISA-95 concepts and manufacturing integration frameworks

Cloud & Analytics Technologies (Preferred)

Experience with one or more of the following:

• Microsoft Azure
• AWS
• Databricks
• Snowflake
• Microsoft Fabric
• Azure Data Factory
• Industrial IoT platforms
• AI and Advanced Analytics solutions

Key Competencies

• Solution Architecture
• Enterprise Integration
• Manufacturing Digitalization
• Data & Analytics Enablement
• IT/OT Convergence
• Cloud & Data Platforms
• Stakeholder Management
• Technical Leadership
• Vendor Management
• Problem Solving
• Communication & Collaboration

Pay Range for this position: $121,500-$182,300

The offer range represents the anticipated low and high end of the base pay compensation for this position. The actual compensation offered will be determined by factors such as location, level of experience, education, skills, and other job-related factors. Position may be eligible for sales or performance-based bonuses. Benefits offered by the Company include health insurance, paid time off (PTO), retirement contributions, and other perquisites. For more information click here.

What we offer: We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress!

Apply now and become a part of a team that is dedicated to Sparking Discovery and Elevating Humanity!