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AI/ML Engineers at Mayo Clinic play a pivotal role in the union of data, systems, and computer sciences. They work closely with a multidisciplinary team, including clinicians, user experience designers, product managers, IT professionals, and external partners, to develop and deploy effective, efficient, and ethical AI/ML solutions into clinical practice to enhance patient care and operational efficiency.
As a Senior Principal AI/ML Engineer, you will lead the full spectrum of the AI life cycle from ideation to production. You understand the clinical environment well, including workflows, challenges, and requirements of healthcare providers and patients. You will leverage advanced techniques in AI/ML to analyze vast amounts of healthcare data, including patient records, medical imaging, and genomic information, and other multimodal data sources, to develop AI solutions that meet clinical needs and are integrated smoothly into clinical processes. This includes guiding the design and evaluation of foundation models, vision encoders, multimodal architectures, representation learning approaches, and data fusion strategies that enable robust clinical AI applications. You will develop, integrate, and standardize software components and create, maintain, and follow quality system procedures. You will guide the engineering of systems that are pivotal to developing and deploying these solutions and provide technical leadership on model architecture decisions, including multimodal learning approaches, model adaptation strategies, evaluation methodologies, interpretability techniques, and performance optimization for clinical AI systems. This will encompass everything from design requirements, development, component creation, verification, non-clinical validation, and risk mitigation to ensure our digital health technology products meet and exceed regulatory requirements and setting new benchmarks for safety and effectiveness in clinical settings. Your expertise will also extend to facilitating consistent and automated AI software solution development and releases through the design, testing, and maintenance of tools and associated CI/CD pipelines.
This role is instrumental in leading consultative services to departments and divisions, offering insights into complex business problems. The role requires deep technical judgment in understanding how AI models learn, represent information, and perform across diverse clinical modalities, enabling informed decisions regarding model design, explainability, reliability, and clinical suitability. Your ability to communicate complex findings in easily understandable terms to non-technical users will bridge the gap between sophisticated AI technologies and clinical applications.
Senior Principal AI/ML Engineers are recognized as top technical authorities in the field of AI/ML and play a critical role in driving innovation and shaping the strategic direction of AI/ML initiatives at Mayo Clinic.
Other Responsibilities May Include:
• Providing strategic direction and technical leadership for AI Engineering initiatives.
• Working with leadership team to define the AI roadmap and prioritize projects aligned with organizational objectives.
• Leading component design, development, integration, and standardization to create AI-driven solutions that seamlessly integrate into clinical practice to enhance patient care and clinic operations.
• Leading the collaboration with multidisciplinary teams, including clinicians, user experience designers, product managers, and IT professionals, to understand user needs, workflows, and clinical requirements and assess feasibility. Translating user feedback and requirements into design concepts and usability specifications for AI solutions.
• Leading the interpretation of data analysis to guide strategic choices and clarify complex insights for non-technical users to connect AI technologies and clinical applications.
• Leading consultative services to clinical work units or AI product teams, offering insights and strategies to address complex business problems.
• Leveraging machine learning techniques such as deep learning, natural language processing, computer vision, multimodal learning, foundation models, and large language models to lead the design, development, and deployment of end-to-end AI solutions for healthcare applications. This includes evaluating and guiding architectural choices involving vision encoders, multimodal fusion approaches, representation learning, and model adaptation strategies.
• Establish rigorous evaluation methodologies and performance metrics to assess the effectiveness, usability, and impact of AI solutions in real-world healthcare settings.
• Ensuring compliance with ethical guidelines, regulatory requirements, and data privacy standards in the development and deployment of AI solutions by the AI development team.
• Overseeing the engineering of systems crucial for developing and deploying AI solutions.
• Facilitating consistent and automated AI software solution development and releases through the design, testing, and maintenance of tools and associated CI/CD pipelines.
• Defining and implementing best practices and standards for AI development and deployment methodologies, tools, and platforms.
• Providing mentorship, guidance, and technical leadership to junior engineers within the AI enablement team. May have supervisory responsibilities.
• Fostering a culture of collaboration, innovation, and knowledge sharing across the organization.
• Supporting talent development initiatives, including training programs, technical workshops, and skill-building activities to enhance team capabilities.
• Contributing to the development of new AI methods and technologies that can advance the state-of-the-art in healthcare AI, including novel approaches in multimodal learning, foundation models, representation learning, computer vision, and clinical AI evaluation.
• Publishing and presenting the results of AI development and translation in peer-reviewed journals and conferences.
This is a full-time remote position within the United States.
Mayo Clinic will not sponsor or transfer visas for this position including F1 OPT STEM.
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