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Simulations Plus

Senior Full-Stack Engineer

Posted a month ago
$90000 - $110K per year
2-5 years experience
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AI Summary

The engineer will own features end-to-end across Node.js backends and React frontends while integrating LLM-powered functionality. They will contribute to data, authentication, and service patterns while collaborating with the AI lead to support product surfaces.

Simulations Plus stands as a global leader in model-informed and AI-accelerated drug development. We create value for our clients by accelerating the discovery, development, and commercialization of pharmaceuticals and other products through innovative science-based software and consulting solutions.

Leadership truly cares about maintaining a positive culture and employee well-being. We offer fully remote work, flexible schedules, and generous vacation policy along with affordable health coverage, annual bonus, and more! Check out how much our employees love working here: https://www.comparably.com/companies/simulations-plus.

The Senior Full-Stack Engineer is a versatile contributor, part of a small department whose charter spans both web/SaaS and AI/agents products. The role will ship features across the full stack — backend, frontend, and LLM-integrated surfaces — wherever the team's most pressing implementation work lands in a given cycle. It's a high-variety role for an engineer who wants to build real depth across web platform and applied-AI engineering, on a deliberately lean team that's growing quickly and intentionally.

Department: Product and Technology 

Internal Grade: 10

Direct Reports: No

Status: Exempt

Location: Remote 

Job Responsibilities:

  • Feature Delivery Across the Stack
    • Own features end-to-end across Node.js and Express backends and React/Tailwind frontends
    • Build the APIs, UI, and data flows behind real customer-facing functionality
    • Contribute to the data, auth, and service patterns the platform builds on
  • AI Feature Integration
    • Integrate LLM-powered functionality into product surfaces, working alongside the team's AI lead
    • Wire frontends to LLM and MCP endpoints; handle streaming, errors, and degraded states gracefully
    • Contribute to evals, fixtures, and tooling that support the AI side of the team
  • Team Impact
    • Bring full-stack range to a team that values flexibility across backend, frontend, and AI
    • Contribute to code reviews, documentation, and the team's shared engineering practices
    • Apply AI coding tools effectively as part of daily engineering workflow
  • Other Duties as Assigned 

Required Qualifications:

  • 3+ years of professional software engineering experience, with shipped full-stack work in production
  • Proficiency in JavaScript or TypeScript across Node.js backend and React frontend
  • Practical experience with document or NoSQL databases such as MongoDB
  • Comfort building and consuming REST APIs and JSON contracts
  • Genuine interest in agents, MCP, and applied AI, and the drive to build real expertise in those areas
  • Fluency using AI coding tools (Claude, Cursor, Copilot) in daily workflow 

Preferred Qualifications:

  • Familiarity with Anthropic, OpenAI, or other LLM provider SDKs
  • Exposure to MCP, agent frameworks, or LLM-integrated product features
  • Experience with cloud infrastructure (AWS preferred) and CI/CD pipelines
  • Experience in regulated-software environments (SOC 2, HIPAA, GxP, 21 CFR Part 11) or life-sciences SaaS
  • Familiarity with Passport, OAuth, OIDC, or comparable auth patterns

Education: 

  • Bachelor's degree in computer science, engineering, or related field preferred
  • Relevant technical certifications welcomed

Come join the happiest employees in the industry by visiting www.simulations-plus.com/career-center and apply today!

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