MDx is a premier full-service laboratory specializing in the analysis, characterization, and quality assurance of pharmaceutical products. We focus on precision and scientific integrity, utilizing industry-leading analytical technology and rigorous methods to deliver results our partners can trust. Collaborating with innovative pharmacists, healthcare providers, and pharmaceutical manufacturers, we advance drug development and safeguard the quality of the therapies that improve lives.

Position Summary

The Systems Engineer plays a critical role in maintaining the security, stability, and performance of our enterprise IT infrastructure across both Microsoft and Apple environments. This position owns the day-to-day administration of Microsoft 365, Entra ID, and Intune, alongside JAMF-based management of our Apple device fleet, ensuring that identity, access, and endpoint compliance are consistently secure and well maintained. Beyond hands-on systems administration, this role provides advanced Tier 2/3 support, leads troubleshooting for complex system issues, and follows disciplined change management practices to keep production environments stable and reliable.

Key Responsibilities

Administer and maintain Microsoft 365 services using Microsoft Admin Center and Entra ID (formerly Azure AD).
Manage user identities, access policies, and Single Sign-On (SSO) configurations
Oversee Microsoft Teams configuration, integration, support, and automation
Implement and manage device compliance and security policies using Microsoft Intune
Administer JAMF for Apple device management, including deployment, configuration, and compliance
Provide Tier 2/3 support for client systems, including Windows and macOS environments
Monitor system performance, troubleshoot issues, and ensure high availability of IT services
Collaborate with cross-functional teams to support IT projects and infrastructure upgrades
Maintain documentation for systems, processes, and configurations
Ensure compliance with IT security policies and best practices
Follow change management procedures for all production system updates, including testing, approval, and rollback planning
Participate in an on-call rotation to respond to critical incidents and after-hours system alerts
Support disaster recovery and business continuity planning, including regular backup verification and recovery testing
Conduct periodic access reviews and audits to maintain least-privilege access across systems

Required Qualifications

4+ years of experience in IT systems administration and/or systems engineering roles across Windows and Apple environments
3+ years of strong hands-on experience with Microsoft Admin Center, Entra ID, and Microsoft Intune
Proficiency in managing Microsoft Teams and configuring SSO solutions
3+ years of experience with JAMF for Apple device lifecycle management
Solid history of client management, endpoint security, and compliance
Familiarity with scripting and automation (e.g., PowerShell, Bash)
Working knowledge of networking fundamentals (DNS, DHCP, VPN, firewalls, and TCP/IP)
Understanding of IT security frameworks and best practices (e.g., least privilege, MFA, patch management, zero trust principles)
Experience with backup, disaster recovery, and business continuity procedures
Experience using a ticketing/ITSM system to track, prioritize, and resolve incidents and requests
Excellent problem-solving skills and attention to detail
Strong communication and documentation abilities
Ability to work independently and manage multiple priorities
Passion for continuous learning and staying current with emerging technologies

Preferred Qualifications

Relevant certifications such as Microsoft Certified: Modern Desktop Administrator, Microsoft 365 Certified: Endpoint Administrator Associate, or JAMF Certified Tech
Security-related certification (e.g., CompTIA Security+)
ITIL Foundation certification or familiarity with ITIL service management practices
Experience with cloud platforms such as Azure or AWS
Experience supporting a hybrid or fully remote workforce
Prior experience in a regulated industry (e.g., healthcare, finance) with associated compliance requirements (e.g., HIPAA, SOC 2)

Work Environment & Physical Requirements

Primarily in a professional office or home office environment, with regular use of computer systems, security monitoring platforms, and forensic analysis tools throughout the workday
Regularly required to sit for extended periods while using a computer, keyboard, and mouse to monitor security systems, investigate incidents, and maintain documentation
Must be able to concentrate for extended periods while analyzing complex security data, often under pressure during active incident response situations that require quick, accurate decision-making
Specific vision abilities required include close vision and the ability to adjust focus for extended periods of screen-based work, including reviewing logs, audit reports, and forensic data
Must be able to communicate clearly and effectively via phone, video conference, and email with IT staff, department leaders, and third-party vendors, including the ability to explain technical security concepts to non-technical audiences
Requires quarterly travel to company locations as needed, which may include time-sensitive travel in response to a security incident requiring on-site presence
Fast-paced environment requiring adaptability and the ability to shift quickly from planned project work to urgent incident response when a security event occurs, sometimes outside of standard business hours

Featured Benefits

Competitive salary
Comprehensive health, dental, and vision insurance
401k with employer match
Paid Time Off
Employee Perks & Discounts

#ReviveRx

$130,000 - $145,000 a year

Why Join MDx?
The best work happens when purpose meets opportunity. At MDx, you'll work with a dedicated, scientifically driven team that's raising the standard for analytical excellence — with the resources, leadership, and culture to back it up. We offer competitive compensation, strong benefits, and real room to grow, lead, and make your mark.

Equal Employment Opportunity (EEO) and Affirmative Action Commitment
MDx is committed to providing equal employment opportunities and render affirmative action to all employees and applicants for employment, including individuals who are members of underrepresented groups, without regard to race, color, religion, gender, sexual orientation, national origin, age, disability, or any other status protected by applicable federal, state, or local laws.

Reasonable Accommodations Statement
To accomplish this job successfully, an individual must be able to perform, with or without reasonable accommodation, each essential function satisfactorily. Reasonable accommodation may be made to help enable qualified individuals with disabilities to perform the essential functions.

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Systems Engineer

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