Director, Commercial Supply Chain

Job Description:

Director, Commercial Supply Chain

The  Director, Commercial Supply Chain will  support the build-out and execution of key commercial supply chain workstreams and help lead the company into its next stage toward the commercialization of our first commercial product, once approved.  This position provides strategic and operational leadership within the commercial supply chain function and is accountable for driving launch readiness planning, scenario planning, and execution of core commercial supply chain workstreams. This includes managing demand/supply/capacity planning, sourcing, labeling, packaging, inventory management, shipping, import/export, and distribution in preparation for commercial launch as well as translating board approved commercial plans into supply volumes and operational plans that align with contractual obligations. This is a unique opportunity to contribute to growth in a dynamic, fast paced environment.

This is a highly cross-functional leadership role for a pre-commercial biotech transitioning from clinical-stage operations to commercial launch. The successful candidate will bring deep pharmaceutical or biotechnology supply chain experience, strong launch readiness discipline, and the ability to build scalable processes in a fast-moving environment.  The Director will partner closely with internal stakeholders and external manufacturing, packaging, and distribution partners.  This role will report to the Senior Director, Global Supply Chain.

Key Responsibilities

Commercial Launch Readiness

• Drive commercial supply chain readiness for the company’s first US product launch, including launch planning, launch cutover, operational readiness, and post-launch stabilization.
• Develop and maintain an integrated commercial supply chain launch plan aligned with regulatory approval timelines, manufacturing release, quality disposition, channel readiness, and customer availability requirements
• Translate board- approved commercial plans into executable launch demand scenarios, supply volume assumptions, inventory strategies, and operational readiness actions.
• Identify launch-critical risks, dependencies, decision points, and mitigation plans across supply planning, distribution, trade, quality, finance, legal, compliance, regulatory, and commercial operations

Supply Planning, Inventory, and S&OP

• Lead development of commercial supply planning processes for demand translation, supply allocation, inventory targets, safety stock, replenishment, expiry management, and launch demand scenarios
• Translate commercial demand plans into supply requirements, forecasts, purchase orders and inventory plans in accordance with applicable supply agreements and contractual obligations.
• Develop inventory strategies that balance patient access, launch uncertainty, working capital, shelf life, and supply continuity
• Monitor performance against supply plans and implement corrective actions to address forecast changes, production constraints, distribution disruptions, or demand variability

Distribution, 3PL, and Channel Operations

• Partner with Market Access, Trade, Finance, Legal, Compliance, and Commercial Operations to support channel strategy, distribution model designs, order-to-cash readiness, and customer experience requirements
• Lead operational readiness and ongoing coordination for key commercial distribution processes, including order management, warehousing, returns, recalls support, temperature control, product allocation, and customer service interfaces
• Ensure distribution and logistics capabilities are scalable, compliant, and aligned with launch requirements and future portfolio needs

Compliance, Quality, and Systems Readiness

• Partner with Quality, Regulatory, Legal, and Compliance to ensure commercial supply chain processes comply with applicable regulations, internal policies, and product quality requirements
• Support serialization, track-and-trace, lot traceability, product security, returns verification, and applicable DSCSA-related readiness activities for US commercialization
• Define business requirements for commercial supply chain systems, master data, reporting, partner integrations
• Support creation, review, and implementation of standard operating procedures, work instructions, training materials, and controlled processes required for commercial operations

Partner and Vendor Management

• Own day-to-day operational management and governance of key external supply chain partners, including 3PL, logistics providers, packaging or labeling partners, and other commercial operations vendors as applicable
• In consultation with the Sr. Director, develop vendor governance routines, performance metrics, business reviews, escalation pathways, and service-level expectations
• Lead issue resolution across external partners and internal stakeholders to protect patient access, supply continuity, and launch timelines
• Support contract input, budget planning, purchase order oversight, invoice review, and operational forecasting for commercial supply chain vendors
• Monitor partner performance against contractual obligations, supply agreements, service levels, forecasts, and launch readiness expectations.

Qualifications

• Bachelor’s degree in supply chain, operations, life sciences, engineering, business, or a related field required; advanced degree preferred
• 10+ years of experience in pharmaceutical, biotechnology, or life sciences supply chain, operations, logistics, manufacturing, or commercial operations
• Direct experience supporting at least one pharmaceutical or biotech product launch in the United States strongly preferred
• Experience managing 3PL, distribution, logistics, specialty pharmacy, specialty distribution, or other commercial supply chain partners
• Strong understanding of GMP/GDP expectations, pharmaceutical distribution requirements, serialization, lot traceability, temperature-controlled logistics, and controlled commercial processes
• Experience building supply chain processes, operating models, vendor governance, launch readiness plans, and cross-functional ways of working in a growing organization
• Demonstrated ability to lead  launch-critical workstreams with a high degree of ownership while partnering closely with senior functional leadership
• Strong analytical, project management, communication, and executive-ready presentation skills
• Comfort operating in an entrepreneurial, pre-commercial environment where processes, systems, and teams are still being built
• Experience anticipating launch risks proactively and driving clear ownership of mitigation actions
• Experience with ERP, planning tools, order management, serialization systems, partner integrations, and/or launch readiness dashboards
• Experience developing S&OP or integrated business planning processes in a pre-commercial or early commercial biotech setting preferred
• Balances strategic design with hands-on execution, is well-organized, proactive and detail oriented
• Location:  This is a U.S. East-coast based, remote-eligible position.  This position will be expected to operate with a high degree of ownership and responsiveness in a virtual, cross-functional environment while maintaining close partnership with internal teams and external partners.  Periodic travel will be required for meetings such as  team meetings, business reviews, partner/site visits, and company meetings

Salary and Benefits:

We offer a competitive base salary, annual bonus, and long-term incentives. In addition, we provide a comprehensive benefits package, including health insurance, dental and vision coverage, term life and disability coverage, and retirement plans.

NewAmsterdam Pharma is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information, or any other basis protected by federal, state or local law.