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Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME, a target expressed in more than 50 cancers. Our cutting-edge science and robust clinical pipeline form the broadest PRAME franchise with the most PRAME indications and modalities, spanning TCR T-cell therapies and TCR bispecifics.
Why Join Us?
Innovative Environment: Help to pioneer advancements in cancer immunotherapy.
Collaborative Culture: Be part of a diverse team dedicated to your professional growth.
Global Impact: Contribute to therapies that make a lasting impact on patients globally.
Role Overview
We are seeking a Director, Clinical Operations Lead to support our Clinical Operations team. The Director, Clinical Operations Lead will be responsible for the oversight, execution, and operational management of global clinical trials in support of our clinical development programs.
Schedule: 8:00 AM – 5:00 PM; Monday to Friday
Reports to: Vice President, Clinical Operations EU
Location: Fully Remote
Salary Range: $215,000.00 - $260,000.00
Basic Qualifications:
Bachelor’s degree
10+ years of demonstrated leadership of global clinical operations in the pharmaceutical or biotechnology industry including clinical trial oversight, vendor management, and cross-functional study leadership
Experience in oncology, cell and/or gene therapy, or other complex biologic clinical development programs
Preferred Qualifications:
Master’s Degree, preferably in life science, nursing, or similar
Demonstrated ability to drive process improvements and operational excellence initiatives
Ability to understand and navigate complex clinical development processes and cross-functional interdependencies
Strong analytical and problem-solving skills with the ability to assess operational impact across broader cross-functional environments
Ability to operate effectively in a fast-paced and evolving clinical development environment
In this role you will:
Lead global clinical trial execution and operational delivery across internal and external stakeholders
Provide oversight of CROs, vendors, and clinical trial partners to ensure quality, compliance, timelines, and budget objectives are achieved
Drive risk identification, issue escalation, and mitigation planning across assigned studies
Support study start up, site feasibility, enrollment, and operational execution activities
Partner cross-functionally with Clinical Development, Regulatory, Safety, Biometrics, Supply Chain, and external vendors
Contribute to SOP development, process optimization, inspection readiness, and operational excellence initiatives
Mentor junior Clinical Operations team members as applicable
Qualified candidates will participate in a structured interview process, which includes:
An initial recruiter phone screen (conducted via video)
A recruiter-facilitated introduction and interview with the hiring leader and key stakeholders (via video)
A final-stage interview, which may include an in-person meeting at our U.S. Headquarters in Houston, TX
What do we offer?
At Immatics, we believe in investing in our team’s health, safety and well-being. Here’s what you can expect if you join Immatics
Comprehensive Benefits:
Competitive rates for Health, Dental, and Vision Insurance
4 weeks of vacation granted up front each year and prorated for first and last year of employment.
12 company paid holidays
7 days of sick time
100% employer-paid life insurance up to at 1x annual salary, up to one hundred thousand dollars
100% employer-paid short- and long-Term disability coverage
401(k) with immediate eligibility and company match…
The company will match 100% of your contributions up to 3% of your base salary for the first two years of employment, 4% for years 2-3 of employment, and up to 5% of your salary from the fourth year onward of continued employment.
Partially paid parental leave for eligible employees.
Additional voluntary employee-paid benefits and services, including accident, hospital indemnity, and critical illness insurance, as well as identity theft protection and pet insurance.
Equal Employment Opportunity
We are an equal opportunity employer and are committed to building a diverse and inclusive workplace. We consider all qualified applicants for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, national origin, ancestry, age, marital status, disability, genetic information, veteran status, or any other status protected by applicable law.
Reasonable Accommodations
We are committed to providing reasonable accommodations to individuals with disabilities and to applicants with sincerely held religious beliefs, practices, or observances. If you require assistance or accommodation during the application or interview process, please contact us at RecruitingUS@immatics.com.
Work Authorization
Applicants must be authorized to work in the United States without the need for current or future sponsorship. Visa sponsorships may be available for certain roles.
Pre-Employment Requirements
Employment is contingent upon successful completion of a background check, reference checks and pre-employment drug screening, where permitted by applicable law. For certain roles, additional screenings such as a credit check or motor vehicle record review may be required, where job-related and consistent with business necessity.
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