Associate Director, Corporate Strategy & Development

Associate Director, Corporate Strategy & Development

About Cabaletta Bio

Cabaletta Bio (Nasdaq: CABA) is a clinical-stage biotechnology company focused on developing and launching the first curative targeted cell therapies designed specifically for patients with autoimmune diseases. The CABA™ platform encompasses two complementary strategies which aim to advance the discovery and development of engineered T cell therapies with the potential to become deep and durable, perhaps curative, treatments for a broad range of autoimmune diseases. The lead CARTA (Chimeric Antigen Receptor T cells for Autoimmunity) strategy is prioritizing the development of rese-cel, a 4-1BB-containing fully human CD19-CAR T cell investigational therapy. Rese-cel is currently being evaluated in the RESET™ (REstoring SElf-Tolerance) clinical development program spanning multiple therapeutic areas, including rheumatology, neurology and dermatology. The company recently presented final phase 1/2 data for rese-cel in myositis and expects to initiate the pivotal myositis trial this year. Cabaletta Bio’s headquarters and labs are based in Philadelphia, PA. For more information, please visit www.cabalettabio.com and connect with us on LinkedIn.

At Cabaletta, we are driven by the shared mission of developing cures, where a patient’s own cells are used to fight disease. We are building a culture grounded in the knowledge that successful cures can be achieved for patients if every member of the Cabaletta is focused on the success of the team. To nurture this, we make an active commitment to the well-being and continuous growth of each employee who joins the team. In this way, we are not only working to improve the lives of patients, but of everyone involved. And we’re proud that for 3 years in a row, we’ve been nationally recognized by Great Place to Work and Fortune as one of the Top 10 Best Small/Medium Workplaces in Biopharma!

Position Summary - Remote

Cabaletta Bio is seeking an Associate Director, Corporate Strategy & Development to join the Corporate Strategy & Business Development team. Reporting to the Chief Business Officer (CBO), this position is responsible for helping define and manage the product pipeline and research strategy, to most effectively address unmet medical need and potential market opportunity.  Additionally, the incumbent in this role supports the CBO in facilitating business development opportunities, inclusive of in-licensing, out-licensing and research collaborations, as well as investor support and public relations.

The successful candidate will combine strong scientific and clinical understanding with strategic and commercial insight to evaluate opportunities across autoimmune diseases and cell therapy. This highly visible role will work cross-functionally with Research, Clinical Development, Regulatory Affairs, Commercial, Finance, Investor Relations, and Executive Leadership to support portfolio prioritization and long-term value creation.

Responsibilities

• Conduct clinical development, competitive, and commercial assessments for existing and potential product candidates across Cabaletta's pipeline.
• Develop revenue forecasts and commercial opportunity assessments for current and future product candidates from launch through lifecycle management.
• Partner with cross-functional stakeholders to evaluate regulatory pathways, standards of care, competitive dynamics, unmet medical need, and market access considerations across target indications.
• Generate strategic recommendations for pipeline prioritization based on scientific rationale, commercial potential, development feasibility, investment requirements, and probability of success.
• Present analyses, recommendations, and business cases to senior leadership and support strategic decision-making processes.
• Support the Chief Business Officer in identifying, negotiating, and executing strategic transactions, including in-licensing, out-licensing, research collaborations, platform partnerships, and other business development opportunities.
• Lead cross-functional diligence teams to efficiently assess external opportunities across academia, biotechnology, and pharmaceutical industries.
• Serve as a subject matter expert for assigned transactions and collaborate closely with operational leaders throughout evaluation and execution.
• Monitor and periodically update assessments of the external landscape, including emerging technologies, competitive programs, potential partnership opportunities, and strategic acquisition targets.
• Support the development of clear, consistent, and compelling communications for investors, analysts, and other external stakeholders regarding Cabaletta's strategy, pipeline, and value proposition.
• Collaborate closely with Investor Relations, Corporate Communications, and Executive Leadership to ensure alignment of strategic messaging.
• Contribute to long-range planning, portfolio management activities, and corporate strategic initiatives.

Qualifications

• Required
  • Bachelor's degree in a scientific, medical, healthcare, business, or related discipline.
  • Minimum of 5–8 years of experience within the biotechnology, pharmaceutical, life sciences, healthcare consulting, investment banking, equity research, business development, corporate strategy, or related fields.
  • Strong understanding of drug development, clinical development, regulatory pathways, and commercialization strategies.
  • Demonstrated ability to evaluate scientific, clinical, commercial, and financial aspects of biotechnology assets and opportunities.
  • Excellent analytical, strategic thinking, and problem-solving capabilities.
  • Outstanding written, verbal, and presentation communication skills.
  • Ability to effectively influence and collaborate across multiple functional areas and organizational levels.
  • Strong business and industry acumen.
  • Outstanding integrity, professionalism, and ethical conduct.
  • Proven ability to manage multiple priorities in a fast-paced and evolving environment.

• Preferred
  • Experience within autoimmune disease, immunology, cell therapy, or related therapeutic areas.
  • Medical, scientific, research, or clinical development experience.
  • Advanced degree such as MD, PhD, PharmD, MBA, or other relevant graduate degree.
  • Prior experience supporting or leading licensing, partnering, merger and acquisition, or strategic collaboration activities.

What We Value

Successful candidates will demonstrate:

• A passion for improving the lives of patients with serious autoimmune diseases.
• A strong team orientation and collaborative mindset.
• Intellectual curiosity and a commitment to continuous learning and self-development.
• A willingness to challenge assumptions and contribute innovative ideas.
• The ability to balance strategic thinking with operational execution.
• A commitment to Cabaletta's values of scientific excellence, integrity, accountability, and patient focus.

Our name – Cabaletta – is derived from the operatic term that represents a rapid, repetitive, and technically challenging section of an operatic aria, where the second act is designed to showcase the skills of the lead singer. Analogously, Cabaletta Bio strives to achieve rapid and repetitive product development, building on our indication prioritization and biologic platform that targets the driver of specific autoimmune diseases without the need for long-term immunosuppression.

For more information, please visit https://www.cabalettabio.com/join-our-crew

Our most important asset is our people, and we offer competitive benefits, PTO, and stock option plans.

Cabaletta Bio is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability, protected veteran status or any other basis protected by applicable law.

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