REMOTE Principal Scientist/Assoc Director In Vivo Pharmacologist

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Posted 2 days ago United States Salary undisclosed
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Job Description

An employer is looking for an Associate Director - In Vivo Oncology, will be responsible for providing support to oncology related discovery teams including planning, designing, conducting/managing, and interpreting experiments to demonstrate effects of novel small molecule conjugates in oncology animal models. The candidate will have a broad background in in vivo pharmacology and oncology.

- Plan, design, conduct, and interpret in vivo experiments to evaluate the efficacy, pharmacokinetics, and safety of therapeutic candidate molecules in support of oncology drug discovery programs

- Develop and implement tumor animal models relevant to specific endocrine-related cancers

- Identify and coordinate contracts with Contract Research Organizations

-Design and manage external studies with Contract Research Organizations

- Demonstrate a high level of initiative to oversee, troubleshoot and accurately perform data analysis on in vivo studies

- Analyze and present experimental data using Prism, Excel, MS Office or comparable software

- Present findings and represent in vivo department to multidisciplinary discovery project teams

- Participate in strategic planning and the evaluation of new targets

- Prepare technical reports to support project reviews, publications, and IND submissions

- Lead and supervise junior scientists

- Responsible for ensuring compliance with company established practices and procedures, including laboratory notebooks, computer files, quality and regulatory guidelines, and safety standards

- Proficiency with basic surgical techniques

- Regulatory experience (GLP)
- Ph.D.inBiology, Neuroscience, Behavioral Pharmacology, Physiology, Endocrinology, or related discipline

- Minimum of 12 years of industry experience.

- Experiencein RadioPharmaceuticals, nuclear medicine, and/or targeted radionuclide therapy is preferredincluding radiochemistry, dosimetry, imaging

- Experienceinconductinginvivopharmacology studies to demonstrate translational efficacyinoncology on Rodents

- Hands on proficiencyinhandling techniquesincluding tumorinoculation and measurement, dosing (IV, PO, SC), blood and tissue collection, necropsy, etc.

- Must beindependent, able to follow pre-established experimental designs, as well as develop new methods, protocols, and technologies based on existing literature

- Experience managing external studies at Contract Research Organizations or having experience working for a CRO